Mechanical ventilator liberation protocol. Recommendation based on review of the evidence

Mechanical ventilation is currently the most widely used supportive therapy for treatment of moderate and severe hypoxemia any etiology. However, decision "when" right time to initiate withdrawal this support a matter debate worldwide. Many authors describe that disconnection process should be gradual in compliance with standards provide safety process; while other report it not feasible establish universal standard since each patient would have unique behavior difficult protocolized manner. The present review represents an extensive search evidence attempt clarify issue, generating from consensus experts at international level, based on broad literature. Keywords: Weaning, Spontaneous breathing trial, Rapid shallow index, P0.1